VISINE is a medication used to relieve eye redness, itching, watery effects and swelling on the eyes which commonly occur due to allergies. It belongs to drug class of sympathomimetic amines which works temporary by narrowing the blood vessels of the eye.
One of the major problem of a urine drug test is adulteration, a practice which involves samples of urine with chemical adulterants to results into a false negative test outcome.This problem evolves the number of chemicals obtained effectively through adulterate specimen of urine.
WHAT HAPPENS DURING DRUG TESTING?
This requires a urine sample being taken to the laboratory. Its best recommended you use a clean catch method. This method involves special techniques such as;Ensure washing of hands appropriately*Using a cleansing pad , clean the genital smoothly*Start to urinate into the toilet ascertain*Allow the urine collection container your urine stream*Collect a certain quantity of urine using the container as marked by your scientist*Return the sample collection container to your laboratory technician.
REASONS FOR A DRUG TEST
Here are some major reasons which may trigger you for a drug test:
Drug regulation
Employment
Sport
Legal purposes
Recover opioid use of a substance
WHAT TO DO WHILE PREPARING FOR THE TEST?
Ensure your lab technician or health care provider is adequately informed if you are still taking a prescribed drugs, because this may hinder an accurate result. Avoid too poppy seed food to as it tends to hinder a good result.
HOW RELIABLE IS A URINE DRUG TEST?
With urine drug test you are sure to have over 99% accuracy of a substance.
WHAT COLOUR SHOULD A URINE BE FOR A DRUG TEST?
The best and recommended for your urine test should be pale yellow. A darker yellow or orange means a patient is dehydrated.
WHAT SUBSTANCES SHOWS UP URINE DRUG TEST?
Urine drug test may be screen for multiple substances ,including methamphetamines, cocaine, opiates, PCP, methadone, benozodiazepines, barbiturates, alcohol ,nicotine.
VISINE IN URINE TO PASS DRUG TEST
Visine contains two chemical ingredient that creates false negatives for THC in urine sample test . Benzalkonium chloride acts as a preservative.
The most active ingredients in visine could cause the retinal blood vessels to shrink physically. Visine is a becomes a better choice ,especially for drug abuse (marijuana )because they carry equal symptoms of redness of the eye.
However, visine wasn’t just detected by a routine urine test and wasn’t effective on glucose -6-phosphate dehydrogenase –drug conjunction.
EXPERIMENT TO PROVE THE EFFECT OF VISINE IN URINE TO PASS DRUG TEST
REF: Public health
Usually people try to cheat drug testing by three different ways: substituting their urine with synthetic urine or drug-free urine purchased from a clandestine source; drinking a commercially available product to flush out drugs; or adding an adulterant in vitro to the urine specimen after collection.
Synthetic urine is difficult to detect because it has similar pH, creatinine, and specific gravity to normal urine. Specific tests are needed to identify compounds that are normal constituents of human urine but not found in synthetic urine, such as cortisol.
Commercially available products that adulterate urine or flush out drugs can be classified under two broad categories. The first includes fluids or tablets that, along with drinking large amounts of water, dilute urine.
Common products are Absolute Detox XXL drink, Absolute Carbo Drinks, Ready Clean Drug Detox Drink, Fast Flush Capsules, and Ready Clean Gel Capsules.
The second category of products is in vitro urinary adulterants that are added to urine after collection. Examples include Stealth (peroxidase and peroxide), Klear (nitrite), Clean ADD-IT-ive (glutaraldehyde) and Urine Luck (pyridinium chlorochromate [PCC]).
In addition, iodine is a strong oxidizing agent and may potentially destroy abused drugs, especially marijuana metabolites
Research also indicates that papain with intrinsic ester hydrolysis ability could significantly reduce the concentration of 11-nor-9-carboxy-9-tetrahydrocannabinol (THC-COOH), a metabolite of marijuana, if added to the urine specimen in vitro Would-be drug test cheaters might try adulterating their specimens with household chemicals, but most can be detected by specimen integrity testing.
Both collection sites and laboratories have at their disposal a number of mechanisms to detect potentially invalid specimens. The temperature, for instance, should be within 90.5–98.9°F.
The specific gravity should be between 1.005–1.030, and pH should be between 4.0–10.0. The creatinine concentration should be 20–400 mg/dL.
However, some drug testing laboratories consider a creatinine concentration of 15 mg/dL as the lower end cutoff. One common adulterant, sodium chloride, always produces a specific gravity greater than 1.035 if added at a concentration necessary to produce a false-negative result.
Unfortunately, specimen integrity testing doesn’t detect all adulterants. For example, it won’t pick up adulteration of urine with Visine eye drops, isopropanol, or other urinary adulterants. However, effective spot tests and special urine dipsticks are available Flushing, Detoxification Agents, and Diuretics
Flushing and detoxification agents are frequently advertised as effective means of passing drug tests. Many of these products contain caffeine or other diuretics to increase the output of urine, as well as sugar and natural or artificial flavoring agents. The objective is to produce diluted urine so that concentrations of abused drugs and or metabolites fall below the recommended cutoff concentrations.
Evaluated the effect of excess fluid ingestion on false-negative marijuana and cocaine urine test results by studying the ability of Naturally Clean Herbal Tea, goldenseal root, and hydrochlorothiazide to cause false negative results.
Volunteers drank one gallon of water, herbal tea, or took hydrochlorothiazide 22 hours after smoking marijuana cigarettes or intranasal administration of cocaine. Their creatinine levels dropped below the cutoff 2 hours after intake of excessive fluid.
Marijuana and cocaine metabolite levels (as measured by both enzyme multiplied immunoassay technique [EMIT] and fluorescence polarization immunoassay [FPIA]) decreased significantly and frequently switched from positive to negative in subjects after consuming 2 quarts of fluid.
Even excess water was effective in diluting a urine specimen to cause false negative results, although herbal tea diluted urine faster compared to water alone.