What Is Rocephin Used For

To answer the question “What is rocephin used for ” First, let’s understand that rocephin is an intravenous and intramuscular antibiotics used to treat health conditions involving any kind of pathogen (bacteria infection) in the urinary tract system, bonds, lungs, skin, joint, abdomen and other areas of the body.

This infections includes; intra-abdominal infections, urinary tract infection, pelvic inflammatory disease, prosthetic joint infection and gonococcal infections.

It also treats life threatening health conditions like pyelonephritis and meningitis. Rocephin is used as a prophylaxis before surgery. Rocephin is a white yellowish- orange crystalline powder.

It also comes in and injectable form. Rocephin is also called Ceftriaxone Sodium. Rocephin is from the class of drugs called cephalosporin. It is available in generic form, the third generation precisely.

In some way, Rocephin is similar to Fetroja. They have same side effects but  definitely do not do the same work as medicines. Rocephin can either be used alone or with other interacting medicines.


Rocephin come in both powder and injection form. The powder form is used for IV solution. Its strengths includes; 250mg, 500mg or 1g, 2g, 10g, 100g. The strengths of the injection form includes; 1g, 2g or 50ml.


Rocephin is supplied as a white to yellowish-orange sterile crystalline powder in a small glass bottle. It is important to note that Rocephin powder should be stored a room temperature of 25°C (77°F) or below. It should not be replaced under any form of light.

The glass bottle contains the following;

  • A glass bottle of 1gm equivalent of ceftriaxone; a box of 1 (NDC 0004-1964-04) and a box of 10 (NDC 0004-1964-01).
  • A glass bottle of 1 gm equivalent of ceftriaxone; a box of 1 (NDC 0004-1963-02) and a box of 10 (NDC 0004-1963-01).


Rocephin are used to treat the following infections and health conditions;

What Is Rocephin Used For
What Is Rocephin Used For

1. Lower Respiratory Tract Infection Caused By;

  • Streptococcus pneumonia
  • Staphylococcus aureus
  • Klebsiella pneumonia
  • Serratia marcescens
  • Enterobacter aerogenes

2. Acute Bacterial Otitis Media Caused By;

  • Streptococcus pneumonia
  • Moraxella catorrhalis
  • Haemophilus influenzae

3. Urinary Tract Infection (Complicated And Uncomplicated) Caused By;

  • Proteus mirabilis
  • Proteus vulgaris
  • Morganella morganii
  • Escherichia coli
  • Klebsiellapneumonia

4. Pelvic Inflammatory Disease (PID) Caused By;

  • Gonorrhea

5. Bacterial Sepsis Caused By;

  • Streptococcus pneumonia
  • Staphylococcus aureus
  • Escherichia coli
  • Klebsiellapneumonia
  • Haemophilus influenzae

6. Rectal Gonorrhea Caused By;

  • Gonorrhea

7. Intra-Abdominal Infection Caused By;

  • Klebsiellapneumonia
  • Escherichia coli
  • Bactericides fragilis
  • Proteus mirabilis
  • Enterobacter Spp.

8. Skin And Soft Tissue Infections Caused By;

  • Streptococcus pneumonia
  • Streptococcus epidermidis
  • Staphylococcus aureus
  • Klebsiella pneumonia
  • Morganella morganii

9. Infections Of The Bones And Joints Caused By;

  • Staphylococcus aureus
  • Streptococcus pneumonia
  • Escherichia coli
  • Proteus mirabilis
  • Enterobaster Spp.

10. Bacterial Meningitis Caused By;

  • Staphylococcus epidermidus
  • Streptococcus pneumonia
  • Escherichia coli
  • Neisseria meningitis
  • Haemophilus influenzae

The right dosage of rocephin for the treatment of the above infection and health conditions is;

  1. 1gm to 2gms daily for intravenous
  2. 2 doses daily divided into 12 hours for intramuscular
  • Animal And Human Bite Wounds: Dosage; 1gm intravenous twice daily interacted with metronidazole or clindamycin.
  • Bacteremia: Dosage; 2gms intravenous twice daily.
  • Bacteria Meningitis: Dosage; 1gm intramuscular as a single dose.
  • Bacterial Peritonitis: Dosage; 2gms intravenous twice daily.
  • Brain Abscess: Dosage; 2gms intravenous twice daily interacted with antibiotics.
  • Chancriod: Dosage;  250gms intravenous as a single dose.
  • Cholecystitis: Dosage; 1gm to 2gms intravenous twice daily for 4 to 7 days.
  • Conjunctivitis: Dosage; 1gm intravenous or intramuscular once daily.
  • Community Acquired Pneumonial: Dosage; 2gms intravenous or intramuscular once daily
  • Endocarditis: Dosage; 1gm intravenous or intramuscular 30 to 60 minutes before procedure.
  • Enteritis: Dosage; 2gms intravenous once daily.
  • Empiric Treatment Caused By HIV: Dosage; 1gm intramuscular as a single dose.
  • Epididymitis: Dosage; 250mg intramuscular as a single dose interacted with doxycycline.
  • Gonococal Meningitis: Dosage1gm intramuscular as a single dose interacted with oral azithromycin.
  • Invasive Meningococal Disease: Dosage; 250mg intramuscular in a single dose.
  • Liver Disease: Dosage; 2gms intravenous once daily.
  • Lyme Disease: Dosage2gms intravenous once daily for about 14 to 28 days.
  • Neurosyphilis In Patients Allergic To Penicillins: Dosage; 2gms intravenous once daily for about 10 to 14 days.
  • Osteomyelitis: Dosage; 2gms intravenous once daily for about 6 weeks.
  • Protocolitis: Dosage; 250mg intramuscular in single dose interacted with oral doxycycline.
  • Prophylaxis For Sexually Transmitted Disease: Dosage; 250mg intramuscular as a single dose interacted with azithromycin and metronidazole or tinidazole.
  • Prothectic Joints Infection: Dosage; 2gms intravenous once daily for about 1 to 6 weeks.
  • Renal Disease: Dosage; 2gms intravenous once daily.
  • Salmonellosis Caused By HIV: Dosage; 1gm intravenous once daily for about 1 to 6 years.
  • Septic Arthritis: Dosage; 1gm to 2gms intravenous once daily.
  • Spontaneous Bacterial Peritonitis: Dosage; 1gm intravenous once daily during active gastrointestinal bleeding for about 7 days.
  • Surgical Site Injection: Dosage; 1gm intravenous 30 minutes to 2 hours before surgery interacted with metronidazole.
  • Typhoid Fever: Dosage; 2gms intravenous twice daily for about 10 to 14 days.
  • Vulvo Vaginitis: Dosage; 1gm intravenous or intramuscular once.
  • Whipple Disease: Dosage; 2gms intravenous once daily for about 10 to 14 days.

The above listed dosage is for adults from 18 and above. For children, your Doctor would prescribe the dosage based on their age.


It is known that people different but it is very rare for Rocephin not to work. However, if Rocephin does not work for you, your Doctor may prescribe an alternative medication for same results.


In a situation where you take an overdose of Rocephin, you cannot reduce it with hemodialysis or peritoneal dialysis. There is no antidote found to treat an overdose of Rocephin so it is rather symptomatic.


Although rocephin treats a lot of health conditions, it also has a whole lot of side effects ranging from common time rare side effects.

Common Side Effects Includes;

  • Chills
  • Cough
  • Fever
  • Diarrhea
  • Sore throat
  • Black stool
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Ulcer
  • Dizziness
  • Swollen glands
  • Fatigue
  • Unusual bleeding
  • Pain at the site of injection, etc.

Rare Side Effects Includes:

  • Blood nose
  • Watery diarrhea
  • Stomach ache
  • Abdominal pain
  • Bleeding gums
  • Bloating
  •  Blood in urine or stool
  • Change in skin color
  • Convulsion
  • Red or dark urine
  • Difficulty in breathing
  • Discomfort
  • Irregular heartbeat
  • Headache
  • Increased sweating
  • Increased thirst
  • Joint inflammation
  • Itching
  • Loss of appetite
  • Muscle pain
  • Cold or flu
  • Nausea or vomiting
  • Pale skin
  • Rash
  • Swelling around eye
  • Redness of the face
  • Tenderness
  • Tightness if the chest.
  • Eosinophilia
  • Swelling of the leg
  • Seizures
  • Unusual weight loss
  • Yellowing of eyes
  • Unpleasant breath odor
  • Skin tightness
  • Loss of taste
  • Pain during sexual intercourse
  • Pass in out gas
  • Skin rash
  • Thick and white vaginal discharge
  • Heartburn
  • Indigestion
  • Red irritated eyes
  • Restlessness
  • Increased serum transaminases
  • Paralysis
  • Leukopenia
  • Overactive reflexes
  • Vomiting

Some of these side effects do not need medical attention, they would go with time as your body gets use to the medicine. Also, your Doctor should be able to tell you ways to prevent or reduce some of these side effects. That is why is good to let your Doctor prescribed it to you or let your Doctor know that you what to take Rocephin so as to guide you well.


There are something you need to do before taking Rocephin. They include;

  • Let your Doctor know about your medical history.
  • Avoid consuming food that have Calcium as they tend to interact with the medicine.
  • Your Doctor has to do a urine test to identify the type of bacteria causing your urinary tract infection.
  • Undergo and Antimicrobial Susceptibility Testing (AST) to know the resistance of bacteria to available antibiotics.
  • Check the ingredients of the medicine to know if you have any allergies.


  • People who are allergic to Rocephin or any of it ingredients.
  • People who are allergic to other types of cephalosporins like cephalaxin.
  • People who are allergic to penicillins like amoxicillin.
  • People who have hypersensitivity reaction
  • People who have anemia.
  • People who have kidney problems.
  • Anyone who just had a surgery.
  • People who have gastrointestinal issues.
  • People who are low in vitamin K.
  • People who have gallbladder disease.
  • People who have stomach or bowel disease.
  • People who have renal impairment.
  • People who are already on medication.
  • A female that is on her menstruation period.
  • A pregnant and breast feeding woman.
  • Children who are not up to 1 year old.


It is important you visit your Doctor if you have any of the dude effects or if after the side effects has been treated, they still persist.


There are lots of brand of Rocephin you can choose from. They include;

  • Aciphin
  • Acrocef
  • Actaxon
  • Alazon
  • Axtar
  • Benaxona
  • Biotriax
  • Brospec
  • Caratan
  • Cet-S
  • Cef-zon
  • Cefaxona
  • Cefizon
  • Cefogram
  • Chef
  • Diacef
  • Ecotrixon
  • Epicephin
  • Excephin
  • Exempla
  • Ferfecef
  • Gemcephin
  • Infecef
  • Ivixone
  • Keptrix
  • Lendacin
  • Langecef
  • Mesporin
  • Monocef
  • Nectram
  • Newcep
  • Nevosef
  • Oncep
  • Pantrixon
  • Power gel
  • Recefin
  • Rocephalin
  • Recephine
  • Roxcef
  • Samixon
  • Socef
  • Tacex
  • Tercef
  • Traxol
  • Triaxone
  • U-Ron
  • Utrixone
  • Vaxel
  • Xone
  • Zeftrox
  • Zeptri
  • Zontrixone


Rocephin is used mostly to treat bacteria infections. Its quick properties and mechanism of action makes it easy to slow down the growth of bacterial cells in the body thereby preventing the emergence of bacterial cells.

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