How Cymbalta Ruined my Life

Over the years, we have had many patients who take Cymbalta leaving more negative reviews about it. Most of these patients are fond of using the phrase CYMBALTA RUINED MY LIFE while some appreciate the positive turn-out effects of Cymbalta.

This article will explore an overview of the drugs, Cymbalta, how Cymbalta ruined my life (including reviews from patients who have used Cymbalta), and other essential details that relate to Cymbalta.


Cymbalta (duloxetine) is a prescription medication that is commonly prescribed for the treatment of various conditions, including depression, anxiety, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. As a serotonin-norepinephrine reuptake inhibitor (SNRI), Cymbalta functions by increasing the levels of serotonin and norepinephrine neurotransmitters in the brain.

Approved by the US Food and Drug Administration (FDA) in 2004, Cymbalta has gained widespread usage throughout the United States. It has been prescribed extensively, and according to data from the IQVIA National Prescription Audit in 2020, it ranked as the 15th most prescribed medication, with over 18 million prescriptions filled.

However, it is important to acknowledge that the use of Cymbalta has experienced a decline in recent years in the United States. This is partly due to increased competition from other antidepressants and pain medications in the market. Furthermore, concerns have been raised regarding the safety and efficacy of Cymbalta, particularly regarding potential withdrawal symptoms and suicidal thoughts. It is crucial to approach these concerns with caution and consult a healthcare professional for personalized guidance.

An overview of Cymbalta can best be discussed herein.


Cymbalta, also referred to as Duloxetine is a medication prescribed for the treatment of various conditions related to nerves and depression.

Cymbalta Ruined my Life
Cymbalta Drugs | How Cymbalta ruined my life

Most of these conditions include:

  • Neuropathic pain
  • Fibromyalgia
  • Generalized anxiety disorder
  • Depressive disorders

Cymbalta belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs). Its mechanism of action involves restoring the balance of neurotransmitters in the brain.

In simpler terms, Cymbalta is utilized to address symptoms of depression, anxiety, and associated nerve-related pain.

It is important to note that any medication intended for the management of mental illness requires proper dosages and regular monitoring under the guidance of a healthcare professional. Incorrect dosages or sudden discontinuation of the drug can result in withdrawal effects.

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It is of utmost importance to emphasize that Cymbalta should never be taken without proper medical consultation. The doses mentioned here are provided as general information and should not be considered personal medical advice. The actual dosage prescribed by your doctor may differ depending on your specific condition. It is crucial to strictly adhere to the prescribed dosage and avoid making any adjustments on your own.

Typically, the initial dose of Cymbalta is 30 mg, as determined by the healthcare provider. Subsequently, the doctor may gradually increase the dosage in increments of 30 mg. Therefore, the dosage can range from 30 mg to higher amounts, such as 60 mg, 90 mg, or even up to 120 mg in certain exceptional cases.

Your doctor will provide specific instructions on how to take Cymbalta. Generally, it is taken orally in the form of a capsule once or twice a day. It is important to swallow the capsule whole and avoid crushing or breaking it.

Remember, always consult your healthcare professional for accurate dosage information and guidance tailored to your individual needs.


Cymbalta can have positive effects on your mood, energy levels, and overall self-confidence. Additionally, it is effective in alleviating nerve pain associated with conditions such as diabetes and peripheral neuropathy.

While using Cymbalta, it is important to be aware of both common and rare side effects that may occur. Let’s explore both categories:

Common side effects of cymbalta:

  • Nausea

Nausea refers to discomfort or uneasiness in the stomach, which can sometimes lead to vomiting if it persists.Nausea is a commonly experienced side effect of many antidepressants, including Cymbalta. Fortunately, for most individuals, the body gradually develops tolerance to this side effect over time. As a result, many people find that the feeling of nausea diminishes or becomes less noticeable as they continue taking the medication.

  • Dry mouth

Cymbalta may lead to a reduction in saliva production, resulting in a dry mouth. A decrease in saliva can contribute to an unpleasant mouth odor. Thankfully, there are simple ways to manage this side effect. One effective method is to stay hydrated by regularly taking sips of water throughout the day. Keeping your mouth moist can help alleviate the discomfort of a dry mouth and minimize any associated odor.

Additionally, practicing good oral hygiene, such as brushing your teeth regularly and using mouthwash, can aid in maintaining a fresh and clean mouth. If the dry mouth persists or becomes bothersome, it is advisable to consult your healthcare provider for further guidance and potential solutions. They may be able to recommend additional strategies or suggest alternative approaches to manage this side effect effectively.

  • Fatigue

Antidepressants, including Cymbalta, can sometimes lead to varying levels of fatigue. This fatigue is often associated with muscle weakness that can result from the medication’s effects

  • Sweating

Experiencing sweating is a common side effect associated with many antidepressant medications, including Cymbalta. This occurrence should not be a cause for significant concern.

  •  Decreased appetite

Cymbalta affects the chemical balance of neurotransmitters in the brain. However, this process can sometimes have unintended effects on other parts of the body. One common effect is a loss of appetite, which can result from the altered chemistry. When a patient’s appetite is affected, they may experience weight loss due to inadequate food intake.

It is important to note that Cymbalta itself does not directly cause weight loss, but rather the reduced food consumption that may occur as a result of the medication’s impact on appetite. Therefore, it is crucial to make an effort to maintain a nutritious diet and ensure an adequate intake of food, even if you may not feel inclined to eat.

If you find that your appetite is significantly affected or if you are experiencing unintended weight loss, it is recommended to discuss these concerns with your healthcare provider. They can provide guidance on managing appetite changes and offer advice on maintaining a healthy and balanced diet while taking Cymbalta.

Rare side effects (although less likely to occur):

  • Allergic reactions like rash or hives
  • Suicidal thoughts or behavior (important to monitor during initial treatment)
  • Serotonin syndrome (a potentially serious condition characterized by agitation, rapid heartbeat, fever, and muscle stiffness)
  • Liver problems (rare, but may cause yellowing of the skin or eyes, dark urine, or persistent abdominal pain)
  • It is essential to discuss any side effects experienced with your doctor to ensure proper management and evaluation of their impact on your well-being.


Withdrawal symptoms and reports of suicidal thoughts and behaviors have been associated with the discontinuation of Cymbalta. Numerous individuals have shared their experiences of severe and prolonged withdrawal symptoms, including sensations of brain zaps, dizziness, nausea, insomnia, anxiety, and irritability. In some cases, these symptoms can persist for weeks or even months.

Furthermore, there have been concerns about Cymbalta’s potential association with an increased risk of suicidal thoughts and behaviors, particularly among young adults and children. As a result, the FDA requires all antidepressants, including Cymbalta, to carry a warning regarding this heightened risk in these specific age groups.

One patient, Angeline, shared her unpleasant experience with the medication. She was prescribed Cymbalta for fibromyalgia pain relief and initially experienced some positive effects. However, after three weeks, she began to encounter severe stomach cramping, nausea, vomiting, migraines, mental confusion, dizziness, high blood pressure, racing heartbeats, depression, nightmares, and heightened startle responses.

Despite discontinuing the medication after three weeks, some of the effects persisted for a month. Angeline strongly advises exercising extreme caution if prescribed Cymbalta and recommends discussing the potential risks and effects thoroughly with physicians before initiating treatment.

In one case, Lettuce shared her daughter’s experience with Cymbalta. Her daughter was initially prescribed the medication for depression, but the dosage was increased to 60mg daily after she was diagnosed with fibromyalgia. Instead of improvement, her daughter experienced increased depression and coordination problems.

She became afraid to ride a bike and started tripping over nothing frequently. It felt like she was constantly wearing rollerblades, requiring her to be cautious while walking. Although the process of discontinuing the medication was difficult, her daughter’s coordination gradually improved. Lettuce emphasized the serious nature of drugs like Cymbalta, which can alter cell structure, and mentioned her daughter’s transition to a natural alternative.

Another user named Littleneck shared his own experience with Cymbalta. After taking 60mg daily for three months, he noticed that his anxiety was worsening. He described a recent incident where he had to abandon a drive with his girlfriend due to being on the verge of a panic attack.

The anxiety persisted throughout the day, preventing him from leaving the house and causing him to miss work. While he felt some relief, he found the prolonged and pronounced nature of his anxiety unusual. He reached out to his doctor’s case worker to discuss this issue at their next appointment.

Finally, Mary shared her experience of fainting three times while taking Cymbalta, which she considers a serious matter. Reflecting on her experience, she regrets not realizing the connection between the fainting episodes and the medication earlier. She acknowledges the need for a thorough investigation of potential side effects and expresses her eagerness to discontinue the drug due to the fear it has caused her.


To minimize the risk of side effects associated with Cymbalta, consider the following recommendations:

  • Adhere to the prescribed dosage provided by your healthcare provider, and avoid exceeding the recommended amount.
  • Discuss any concerns or inquiries about the medication with your healthcare provider to ensure a clear understanding.
  • Refrain from consuming alcohol while taking Cymbalta, as it can heighten the likelihood of experiencing side effects.
  • Inform your healthcare provider about all other medications or supplements you are currently taking, as they may interact with Cymbalta.
  • Do not abruptly discontinue Cymbalta without consulting your healthcare provider, as this may lead to withdrawal symptoms. Follow their guidance for gradual tapering.
  • If you encounter worrisome symptoms like suicidal thoughts or behaviors, breathing difficulties, severe headaches, or seizures, contact your healthcare provider immediately.
  • Regularly attend follow-up appointments with your healthcare provider to assess your response to the medication and monitor any potential side effects.


It is essential to be aware of the potential risks and side effects associated with Cymbalta, as well as to closely communicate any concerns or experiences to healthcare professionals. They can provide guidance, support, and potential alternatives to ensure your well-being and safety throughout the treatment process.



Yes, Cymbalta carries a potential risk for misuse and dependence.


A significant number of individuals who opt for Cymbalta to address mental health conditions and chronic pain decide to undergo long-term treatment. However, there are instances where your doctor might discontinue the prescription of Cymbalta.

Alternatively, you may personally choose to discontinue its usage if you find that it no longer provides the desired effectiveness or if you experience adverse side effects. It is important to consult with your healthcare provider before making any decisions regarding the continuation or cessation of Cymbalta.


“Cymbalta (Duloxetine): everything you need to know”,, accessed May 19, 2023,

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